Built in 1855 as the district church for the township of Over Tabley and part of the township of Mere (previously served by Rostherne: St. Mary). The boundaries of "The District of Over Tabley" were described in the London Gazette on 6 November 1855:
"The district chapelry of Over Tabley is bounded by a line commencing at the northern extremity of such district chapelry at the point where the boundary line of the townships of High Legh and Mere meet in the cross roads at the north-west of Yew Tree House, and proceeding in a south-westerly direction along the boundary line separating those townships untill it reaches the parish of Great Budworth, then proceeding in a southerly, easterly, and again in a southerly direction along the boundary line separating the said parish of Great Budworth from the said parish of Rostherne, until it meets the parish of Knutsford, and then proceeding in an easterly and northerly direction along the boundary line separating the said parishes of Rostherne and Knutsford, unt il such boundary line reaches the wall of Tatton-park, then proceeding northerly along the western side of that wall to the point where the boundary line of the townships of Over Tabley, Mere, and Tatton meet, then proceeding in a north-westerly direction along the boundary line of the said townships of Mere and Tatton to the place where the said boundary takes a northwardly direction (about forty yards from the east side of the Altrincham Turnpike-road) thence in a westwardly direction towards the said road, thence in a northwardly direction up the centre of the said road about one hundred and fifty yards, thence in a south-westwardly direction along the centre of a certain highway to the "Warrington and Knutsford Turnpike-road, and thence along the centre of the said turnpike-road to the first-named point near to Yew Tree House, where the boundary line of the said district chapelry commenced".
The district was affected by the following boundary changes:
- 1968 November 22 — (details not available)
- 1973 June 20 — (details not available)
C = Christenings (Baptisms) ; M = Marriages ; B = Burials ; BTs = Bishop's Transcripts